BDBM534842 US11236052, Compound ID #2::US12076401, Compound ID#25

SMILES ONC(=O)c1ccc(Nc2nc3ccccc3n2C2CCCCC2)cc1

InChI Key InChIKey=GLWKVGFPAGPIKY-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 534842   

TargetHistone deacetylase 1(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2 | US12076401, Compound ...)
Affinity DataIC50: 385nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2 | US12076401, Compound ...)
Affinity DataIC50: 68nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2 | US12076401, Compound ...)
Affinity DataIC50: 15nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2 | US12076401, Compound ...)
Affinity DataIC50: 3.56E+3nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2 | US12076401, Compound ...)
Affinity DataIC50: 385nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2 | US12076401, Compound ...)
Affinity DataIC50: 68nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2 | US12076401, Compound ...)
Affinity DataIC50: 15nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2 | US12076401, Compound ...)
Affinity DataIC50: 3.56E+3nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
Go to US Patent