BDBM534633 N-(6-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methyl-5-oxo-5,6,7,8-tetrahydroquinolin-::US11229636, Compound 46

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3C(=O)C(C)(CCc3n2)n2nc(C)cc2C)cc1

InChI Key InChIKey=SLRVPBFSGVOFDP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534633   

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534633(US11229636, Compound 46 | N-(6-(3,5-dimethyl-1H-py...)
Affinity DataIC50: 300nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
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