BDBM534617 2-(4-(ethylsulfonyl)phenyl)-N-(6-methyl-6-(2-methylimidazo[1,2-a]pyrazin-8-yl)-::US11229636, Compound 105::US11229636, Compound 9

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3C(=O)C(C)(CCc3n2)c2nccn3cc(C)nc23)cc1

InChI Key InChIKey=JRQGFFDDCUGJTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534617   

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534617(US11229636, Compound 105 | 2-(4-(ethylsulfonyl)phe...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534617(US11229636, Compound 105 | 2-(4-(ethylsulfonyl)phe...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
US Patent