BDBM534614 2-(4-(ethylsulfonyl)phenyl)-N-(6-(6-methoxypyridin-3-yl)-6-methyl-5-oxo-::US11229636, Compound 2

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3C(=O)C(C)(CCc3n2)c2ccc(OC)nc2)cc1

InChI Key InChIKey=BAYACCYDWNOYFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534614   

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534614(US11229636, Compound 2 | 2-(4-(ethylsulfonyl)pheny...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
US Patent