BDBM53452 2-[4-(4-Fluoro-phenyl)-thiazol-2-ylamino]-2-[1-(4-methyl-benzyl)-1H-benzoimidazol-2-yl]-ethanol::2-[[4-(4-fluorophenyl)-1,3-thiazol-2-yl]amino]-2-[1-[(4-methylphenyl)methyl]benzimidazol-2-yl]ethanol::2-[[4-(4-fluorophenyl)-2-thiazolyl]amino]-2-[1-[(4-methylphenyl)methyl]-2-benzimidazolyl]ethanol::2-[[4-(4-fluorophenyl)thiazol-2-yl]amino]-2-[1-(4-methylbenzyl)benzimidazol-2-yl]ethanol::MLS000911893::O-acyl oxime isatin derivative, 17::SMR000478120::cid_23724090

SMILES Cc1ccc(Cn2c(nc3ccccc23)C(CO)Nc2nc(cs2)-c2ccc(F)cc2)cc1

InChI Key InChIKey=PNLLPSRETNSELK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 53452   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Mouse)
Brigham and Women'S Hospital

LigandPNGBDBM53452(2-[4-(4-Fluoro-phenyl)-thiazol-2-ylamino]-2-[1-(4-...)
Affinity DataIC50: 8.80E+3nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2011
Entry Details Article
PubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53452(2-[4-(4-Fluoro-phenyl)-thiazol-2-ylamino]-2-[1-(4-...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay