BDBM534145 4,6-Dimethyl-N-(2-methylquinoline-8-sulfonyl)-1-benzofuran-2-carboxamide ::WO2022081842, Example 21

SMILES Cc1cc(C)c2cc(oc2c1)C(=O)NS(=O)(=O)c1cccc2ccc(C)nc12

InChI Key InChIKey=FWJNOAGBHWWTBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534145   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandPNGBDBM534145(WO2022081842, Example 21 | 4,6-Dimethyl-N-(2-methy...)
Affinity DataIC50: 27nMAssay Description: Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842

TargetHistone acetyltransferase KAT6B(Human)
The Broad Institute

WIPO
LigandPNGBDBM534145(WO2022081842, Example 21 | 4,6-Dimethyl-N-(2-methy...)
Affinity DataIC50: 53nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842