BDBM534021 WO2022081807, Example 128

SMILES COc1ccc(cc1S(=O)(=O)NC(=O)c1cc2c(F)cc(cc2o1)N1CCC1)C(C)C

InChI Key InChIKey=JBVLNGFJNDPCRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534021   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandPNGBDBM534021(WO2022081807, Example 128)
Affinity DataIC50: 8.15nMAssay Description:Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081807

TargetHistone acetyltransferase KAT6B(Human)
The Broad Institute

WIPO
LigandPNGBDBM534021(WO2022081807, Example 128)
Affinity DataIC50: 15nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081807