BDBM533493 (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)- 5-((R)-1-(4-chloro-3-methylphenyl)-1- hydroxyethyl)tetrahydrofuran-3,4-diol::US11220524, Example 2-C

SMILES Cc1cc(ccc1Cl)[C@@](C)(O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=FQHZZVSKMGNOFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533493   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM533493(US11220524, Example 2-C | (2R,3R,4S,5S)-2-(6-amino...)
Affinity DataIC50: 13.5nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent