BDBM533491 (E)-7-((1R,2S,3R,4S)-4-((S)-1-(3,4- dichlorophenyl)-1-hydroxyethyl)- 2,3-dihydroxycyclopentyl)-1,7- dihydro-4H-pyrrolo[2,3- d]pyrimidin-4-one oxime::US11220524, Example 94-B

SMILES C[C@](O)([C@H]1C[C@H]([C@H](O)[C@@H]1O)n1ccc2c1[nH]cn\c2=N\O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=XDSGZKIAGNIVDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533491   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM533491(US11220524, Example 94-B | (E)-7-((1R,2S,3R,4S)-4-...)
Affinity DataIC50: 3.40nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2022
Entry Details
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