BDBM533486 (Z)-7-((1R,2S,3R,4S)-4-(2-(2- ((cyclopropylmethyl)amino)quinolin- 7-yl)ethyl)-2,3- dihydroxycyclopentyl)-1,7-dihydro- 4H-pyrrolo[2,3-d]pyrimidin-4-one O-methyl oxime::US11220524, Example 90-B

SMILES CO\N=c1/nc[nH]c2n(ccc12)[C@@H]1C[C@H](CCc2ccc3ccc(NCC4CC4)nc3c2)[C@@H](O)[C@H]1O

InChI Key InChIKey=CQOJYBCVEDQRIV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533486   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM533486(US11220524, Example 90-B | (Z)-7-((1R,2S,3R,4S)-4-...)
Affinity DataIC50: 0.820nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
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