BDBM533477 (Z)-7-((1R,2S,3R,4S)-2,3-dihydroxy- 4-(2-(2-(methylamino)quinolin-7- yl)ethyl)cyclopentyl)-1,7-dihydro- 4H-pyrrolo[2,3-d]pyrimidin-4-one O-methyl oxime::US11220524, Example 84-B

SMILES CNc1ccc2ccc(CC[C@H]3C[C@H]([C@H](O)[C@@H]3O)n3ccc4c3[nH]cn\c4=N/OC)cc2n1

InChI Key InChIKey=AGOIKKPEOPSIHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533477   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM533477(US11220524, Example 84-B | (Z)-7-((1R,2S,3R,4S)-2,...)
Affinity DataIC50: 2.70nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
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