BDBM533476 (1S,2R,3S,5R)-3-(2-(2- ((cyclopropylmethyl)amino)quinolin- 7-yl)ethyl)-5-(4-(1- methylhydrazineyl)-7H-pyrrolo[2,3- d]pyrimidin-7-yl)cyclopentane-1,2- diol::US11220524, Example 79-B

SMILES CN(N)c1ncnc2n(ccc12)[C@@H]1C[C@H](CCc2ccc3ccc(NCC4CC4)nc3c2)[C@@H](O)[C@H]1O

InChI Key InChIKey=ADMXDABBLUUEPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533476   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM533476(US11220524, Example 79-B | (1S,2R,3S,5R)-3-(2-(2- ...)
Affinity DataIC50: 8.20nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent