BDBM533465 US11220494, Example F21

SMILES C[C@H](O)C(=O)N1CC[C@@H](Nc2ncc(Cl)c(n2)-c2cc(Cl)c3ncn(c3c2)C(C)(C)C)[C@H](O)C1

InChI Key InChIKey=YJXCLPMUNHAMQF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 533465   

LigandPNGBDBM533465(US11220494, Example F21)
Affinity DataKi:  0.400nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM533465(US11220494, Example F21)
Affinity DataKi:  7.70nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent