BDBM533464 (E)-7-((2R,3R,4S,5S)-5-((1R)-1-(3,4- dichlorocyclohexa-2,4-dien-1-yl)-1- hydroxyethyl)-3,4-dihydroxytetrahydrofuran- 2-yl)-1,7-dihydro-4H-pyrrolo[2,3- d]pyrimidin-4-one oxime::US11220524, Example 105

SMILES C[C@](O)([C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c1[nH]cn\c2=N\O)C1CC=C(Cl)C(Cl)=C1

InChI Key InChIKey=XXYWLEVHJQGNLG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533464   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM533464(US11220524, Example 105 | (E)-7-((2R,3R,4S,5S)-5-(...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
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