BDBM533461 (Z)-7-((2R,3R,4S,5R)-5-((R)-(3,4- dichlorophenyl)(hydroxy)methyl)-3,4- dihydroxytetrahydrofuran-2-yl)-1,4a,7,7a- tetrahydro-4H-pyrrolo[2,3-d]pyrimidin-4- one O-(2,2,2-trifluoroethyl)oxime::US11220524, Example 103

SMILES O[C@@H]([C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c1[nH]cn\c2=N/OCC(F)(F)F)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=MGSHKRIIABUSCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533461   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM533461(US11220524, Example 103 | (Z)-7-((2R,3R,4S,5R)-5-(...)
Affinity DataIC50: 29.6nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2022
Entry Details
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