BDBM533443 7-((2R,3R,4S)-5-((R)-1-(4-chlorophenyl)-1- hydroxyethyl)-3,4-dihydroxytetrahydrofuran- 2-yl)-1,7-dihydro-4H-pyrrolo[2,3- d]pyrimidin-4-one O-ethyl oxime::US11220524, Example 83

SMILES CCO\N=c1/nc[nH]c2n(ccc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)[C@](C)(O)c1ccc(Cl)cc1

InChI Key InChIKey=KWIOEMTZPKAQPU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533443   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM533443(US11220524, Example 83 | 7-((2R,3R,4S)-5-((R)-1-(4...)
Affinity DataIC50: 29.1nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2022
Entry Details
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