BDBM533440 (2R,3S,4R,5R)-2-((R)-(3,4- dichlorophenyl)(hydroxy)methyl)-5-((Z)-4-(2- methylhydrazineylidene)-1,4-dihydro-7H- pyrrolo[2,3-d]pyrimidin-7- yl)tetrahydrofuran-3,4-diol::US11220524, Example 81

SMILES CN\N=c1/nc[nH]c2n(ccc12)[C@@H]1O[C@H]([C@H](O)c2ccc(Cl)c(Cl)c2)[C@@H](O)[C@H]1O

InChI Key InChIKey=SJVIZOJFYFICDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533440   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM533440(US11220524, Example 81 | (2R,3S,4R,5R)-2-((R)-(3,4...)
Affinity DataIC50: 0.300nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
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