BDBM533434 7-((2R,3R,4S,5S)-5-((R)-1-(3,4- dichlorophenyl)-1-hydroxyethyl)-3,4- dihydroxytetrahydrofuran-2-yl)-1,7-dihydro- 4H-pyrrolo[2,3-d]pyrimidin-4-one O-methyl oxime::US11220524, Example 61

SMILES CO\N=c1/nc[nH]c2n(ccc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)[C@](C)(O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=HVVYGSDCWYHXPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533434   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM533434(US11220524, Example 61 | 7-((2R,3R,4S,5S)-5-((R)-1...)
Affinity DataIC50: 2.60nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2022
Entry Details
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