BDBM533433 7-((2R,3R,4S,5R)-5-((R)-(3-fluoro-4- (trifluoromethyl)phenyl)(hydroxy)methyl)- 3,4-dihydroxytetrahydrofuran-2-yl)-1,7- dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one O-methyl oxime::US11220524, Example 78

SMILES CO\N=c1\nc[nH]c2n(ccc12)[C@@H]1O[C@H]([C@H](O)c2ccc(c(F)c2)C(F)(F)F)[C@@H](O)[C@H]1O

InChI Key InChIKey=NZHNTAQIEXXLET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533433   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM533433(US11220524, Example 78 | 7-((2R,3R,4S,5R)-5-((R)-(...)
Affinity DataIC50: 3.10nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2022
Entry Details
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