BDBM533424 7-((2R,3R,4S,5R)-5-((R)-(4- chlorophenyl)(hydroxy)methyl)-3,4- dihydroxytetrahydrofuran-2-yl)-5-fluoro-1,7- dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one oxime::US11220524, Example 72

SMILES O\N=c1\nc[nH]c2n(cc(F)c12)[C@@H]1O[C@H]([C@H](O)c2ccc(Cl)cc2)[C@@H](O)[C@H]1O

InChI Key InChIKey=YNNRDSIFCSVIDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533424   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM533424(US11220524, Example 72 | 7-((2R,3R,4S,5R)-5-((R)-(...)
Affinity DataIC50: 2.80nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2022
Entry Details
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