BDBM533422 7-((2R,3R,4S,5R)-5-((R)-(4- chlorophenyl)(hydroxy)methyl)-3,4- dihydroxytetrahydrofuran-2-yl)-2-methyl- 1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4- one oxime::US11220524, Example 71

SMILES Cc1n\c(=N/O)c2ccn([C@@H]3O[C@H]([C@H](O)c4ccc(Cl)cc4)[C@@H](O)[C@H]3O)c2[nH]1

InChI Key InChIKey=IPYAEANWZBKIHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533422   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM533422(US11220524, Example 71 | 7-((2R,3R,4S,5R)-5-((R)-(...)
Affinity DataIC50: 13.9nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2022
Entry Details
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