BDBM5325 3-(5-Thien-3-ylpyridin-3-yl)-1Hindole 3h::dimethyl[2-({3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-indol-1-yl}methyl)propyl]amine

SMILES CC(CN(C)C)Cn1cc(-c2cncc(c2)-c2ccsc2)c2ccccc12

InChI Key InChIKey=QQOJRBANIUPIQJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5325   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM5325(dimethyl[2-({3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-...)
Affinity DataIC50: 46nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed