BDBM532363 US11214540, Example 21::US11214540, Example 65

SMILES [#6]\[#6](-[#6])=[#6]\[#6](-[#6]-[#6]-c1ccc(F)cc1)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-[#6]-1-[#6]-[#6]-[#8]-[#6]-[#6]-1

InChI Key InChIKey=YENDJSIKOTYARX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 532363   

TargetSigma intracellular receptor 2(Rat)
Cognition Therapeutics

US Patent
LigandPNGBDBM532363(US11214540, Example 65 | US11214540, Example 21)
Affinity DataKi:  6.20nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Cognition Therapeutics

US Patent
LigandPNGBDBM532363(US11214540, Example 65 | US11214540, Example 21)
Affinity DataKi:  8nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Rat)
Cognition Therapeutics

US Patent
LigandPNGBDBM532363(US11214540, Example 65 | US11214540, Example 21)
Affinity DataKi:  270nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Cognition Therapeutics

US Patent
LigandPNGBDBM532363(US11214540, Example 65 | US11214540, Example 21)
Affinity DataKi:  1.20E+3nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
Go to US Patent