BDBM532331 (S)-3-((1-(1-(2,3-dihydrobenzofuran-6-yl)ethyl)piperidin-4-yl)oxy)pyridine and (R)-3-((1-(1-(2,3-dihydrobenzofuran-6-yl)ethyl)piperidin-4-yl)oxy)pyridine::US11213525, Example 28::US11213525, Example 39

SMILES CC(N1CCC(CC1)Oc1cccnc1)c1ccc2CCOc2c1

InChI Key InChIKey=GVJKIZFGIYGORW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 532331   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM532331((S)-3-((1-(1-(2,3-dihydrobenzofuran-6-yl)ethyl)pip...)
Affinity DataIC50: 50nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM532331((S)-3-((1-(1-(2,3-dihydrobenzofuran-6-yl)ethyl)pip...)
Affinity DataIC50: 5.50E+3nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent