BDBM532275 4-[2-[(2-Methylpyrazol-3-yl)amino]-4-pyridyl]-6-[2-(trifluoromethyl)phenyl]-1H-pyridin-2-one::US11208423, Example 50::US11780858, Example 50

SMILES Cn1nccc1Nc1cc(ccn1)-c1cc([nH]c(=O)c1)-c1ccccc1C(F)(F)F

InChI Key InChIKey=JFPPAKQKQSEFDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 532275   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandPNGBDBM532275(4-[2-[(2-Methylpyrazol-3-yl)amino]-4-pyridyl]-6-[2...)
Affinity DataIC50: 55nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
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TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandPNGBDBM532275(4-[2-[(2-Methylpyrazol-3-yl)amino]-4-pyridyl]-6-[2...)
Affinity DataIC50: 55nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent