BDBM532265 4-(2-anilinopyrimidin-4-yl)-6-morpholino-1H-pyridin-2-one::US11208423, Example 10::US11780858, Example 10

SMILES O=c1cc(cc([nH]1)N1CCOCC1)-c1ccnc(Nc2ccccc2)n1

InChI Key InChIKey=OWCOKHBOLFYWHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 532265   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandPNGBDBM532265(4-(2-anilinopyrimidin-4-yl)-6-morpholino-1H-pyridi...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandPNGBDBM532265(4-(2-anilinopyrimidin-4-yl)-6-morpholino-1H-pyridi...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent