BDBM532200 (2R,3S,4R,5R)-2- (4-chloro-2- (hydroxymethyl)- benzyl)-3-methyl-5- (4-methyl-7H- pyrrolo[2,3-d]- pyrimidin-7-yl)tetra- hydrofuran-3,4-diol::US11208416, Example 64

SMILES Cc1ncnc2n(ccc12)[C@@H]1OC(Cc2ccc(Cl)cc2CO)[C@@](C)(O)[C@H]1O

InChI Key InChIKey=ZGTFXCLQCUFVNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532200   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM532200((2R,3S,4R,5R)-2- (4-chloro-2- (hydroxymethyl)- ben...)
Affinity DataIC50: 1.61E+3nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
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