BDBM532164 (2S,3S,4R,5R)-5-(4- amino-7H-pyrrolo- [2,3-d]pyrimidin-7- yl)-3-methyl-2- ((methylthio)methyl)- tetrahydrofuran-3,4- diol::US11208416, Example 17

SMILES CSC[C@H]1OC([C@H](O)[C@]1(C)O)n1ccc2c(N)ncnc12

InChI Key InChIKey=LQQSOCLYTRMQNW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532164   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM532164((2S,3S,4R,5R)-5-(4- amino-7H-pyrrolo- [2,3-d]pyrim...)
Affinity DataIC50: 900nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent