BDBM532112 US11208418, Example 1

SMILES CC1(C)Cc2ccc(cc2Oc2ccc(OCc3c(onc3-c3c(Cl)cccc3Cl)C3CC3)nc12)C(O)=O

InChI Key InChIKey=MNKOCHGIHQJVHB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 532112   

TargetBile acid receptor(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM532112(US11208418, Example 1)
Affinity DataEC50:  3.40nMAssay Description:Purchasing Invitrogen PV4833 Kit.Step 1, the compound was weighed and dissolved in 100% DMSO, the highest concentration is 3000 μM, and then dil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM532112(US11208418, Example 1)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at FXR (unknown origin) incubated for 15 mins by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed