BDBM5319 3-(5-Thien-3-ylpyridin-3-yl)-1Hindole 3b::dimethyl(2-{3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-indol-1-yl}ethyl)amine

SMILES CN(C)CCn1cc(-c2cncc(c2)-c2ccsc2)c2ccccc12

InChI Key InChIKey=KHMGHCIGLDWGQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5319   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM5319(dimethyl(2-{3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-i...)
Affinity DataIC50: 115nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM5319(dimethyl(2-{3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-i...)
Affinity DataIC50: 115nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed