BDBM5318 3-(5-Thien-3-ylpyridin-3-yl)-1Hindole 3a::3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-indole

SMILES c1cc(cs1)-c1cncc(c1)-c1c[nH]c2ccccc12

InChI Key InChIKey=GDLQJKCZVIUEDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5318   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM5318(3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-indole | 3-(5...)
Affinity DataIC50: 126nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM5318(3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-indole | 3-(5...)
Affinity DataIC50: 126nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed