BDBM531677 6-(4-chloro-3,5-dimethyl-1H-pyrazol-1-yl)-N-{1-(cyclopropylmethyl)-4-methyl-3-[4-(trifluoromethoxy)phenyl]-1H-pyrazol-5-yl}pyrimidin-4-amine::US11208400, Example 310

SMILES O=c1c(N2CCOCC2)c(N(Cc2ccc(-c3nnc(C(F)(F)F)o3)cc2)c2ccccc2)c1=O

InChI Key InChIKey=VAAUKVJCHWTMCB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 531677   

TargetHistone deacetylase 6(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 531677BDBM531677(Synthesis of 3-morpholino-4-[N-[[4-[5-(trifluorome...)
Affinity DataIC50: 161nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetHistone deacetylase 1(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 531677BDBM531677(Synthesis of 3-morpholino-4-[N-[[4-[5-(trifluorome...)
Affinity DataIC50: 1.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent