BDBM531672 N-{1-(cyclopropylmethyl)-3-[4-(difluoromethyl)phenyl]-4-methyl-1H-pyrazol-5-yl}-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-amine::US11208400, Example 305

SMILES CN1CCN(c2c(N(Cc3ccc(-c4nnc(C(F)F)o4)cn3)c3cccc(-c4ccncc4)c3)c(=O)c2=O)CC1

InChI Key InChIKey=WCVHYDOKDYQUGJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 531672   

TargetHistone deacetylase 6(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 531672BDBM531672(Synthesis of 3-(((5-(5-(difluoromethyl)-1,3,4-oxad...)
Affinity DataIC50: 102nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetHistone deacetylase 1(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 531672BDBM531672(Synthesis of 3-(((5-(5-(difluoromethyl)-1,3,4-oxad...)
Affinity DataIC50: 1.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent