BDBM531665 4-[5-({6-[4-(2-hydroxypropan-2-yl)-3,5-dimethyl-1H-pyrazol-1-yl]pyrimidin-4-yl}amino)-1,4-dimethyl-1H-pyrazol-3-yl]benzonitrile::US11208400, Example 298

SMILES CN1CCN(c2c(N(Cc3ccc(-c4nnc(C(F)F)o4)cc3F)c3cccc(Br)c3)c(=O)c2=O)CC1

InChI Key InChIKey=CWZRHBGTOXPTJK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 531665   

TargetHistone deacetylase 6(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 531665BDBM531665(US20260028321, Compound 12)
Affinity DataIC50: 30nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetHistone deacetylase 1(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 531665BDBM531665(US20260028321, Compound 12)
Affinity DataIC50: 1.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent