BDBM531664 6-{3,5-dimethyl-4-[(4-methylpiperazin-1-yl)methyl]-1H-pyrazol-1-yl}-N-[4-ethyl-5-(4-fluorophenyl)-1-methyl-1H-pyrazol-3-yl]pyrimidin-4-amine::US11208400, Example 297

SMILES CN1CC2(C1)CN(c1c(N(Cc3ccc(-c4nnc(C(F)F)o4)cc3)c3ccccc3)c(=O)c1=O)C2

InChI Key InChIKey=WYLKPDVKMDLWPL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 531664   

TargetHistone deacetylase 6(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 531664BDBM531664(US20260028321, Compound 11)
Affinity DataIC50: 60nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetHistone deacetylase 1(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 531664BDBM531664(US20260028321, Compound 11)
Affinity DataIC50: 1.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent