BDBM531662 2-[1-(6-{[1-(cyclopropylmethyl)-3-(4-fluorophenyl)-4-methyl-1H-pyrazol-5-yl]amino}pyrimidin-4-yl)-3,5-dimethyl-1H-pyrazol-4-yl]-1,1,1,3,3,3-hexafluoropropan-2-ol::US11208400, Example 295

SMILES CN1CCN(c2c(N(Cc3ccc(-c4nnc(C(F)F)o4)cc3F)c3cc(F)cc(-c4ccncc4)c3)c(=O)c2=O)CC1

InChI Key InChIKey=FRYBYMBOTVBFQV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 531662   

TargetHistone deacetylase 6(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 531662BDBM531662(Synthesis of 3-((4-(5-(difluoromethyl)-1,3,4-oxadi...)
Affinity DataIC50: 54nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetHistone deacetylase 1(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 531662BDBM531662(Synthesis of 3-((4-(5-(difluoromethyl)-1,3,4-oxadi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent