BDBM531659 2-{1-[6-({1-(cyclopropylmethyl)-4-methyl-3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}amino)pyrimidin-4-yl]-3,5-dimethyl-1H-pyrazol-4-yl}propan-2-ol::US11208400, Example 292

SMILES O=c1c(N2CCS(=O)(=O)CC2)c(N(Cc2ncc(-c3nnc(C(F)F)o3)cc2F)c2ccccc2)c1=O

InChI Key InChIKey=YVADIBIVQXFKPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 531659   

TargetHistone deacetylase 6(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 531659BDBM531659(Synthesis of 3-(((5-(5-(difluoromethyl)-1,3,4-oxad...)
Affinity DataIC50: 32nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetHistone deacetylase 1(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 531659BDBM531659(Synthesis of 3-(((5-(5-(difluoromethyl)-1,3,4-oxad...)
Affinity DataIC50: 1.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent