BDBM53163 (3E)-5-bromo-1H-indole-2,3-dione 3-[(3-methylphenyl)hydrazone]::5-bromanyl-3-[2-(3-methylphenyl)hydrazinyl]indol-2-one::5-bromo-3-[(3-methylphenyl)hydrazo]-2-indolone::5-bromo-3-[2-(3-methylphenyl)hydrazinyl]indol-2-one::5-bromo-3-[N'-(m-tolyl)hydrazino]indol-2-one::MLS001201321::SMR000564051::cid_5967902

SMILES Cc1cccc(NNC2=c3cc(Br)ccc3=NC2=O)c1

InChI Key InChIKey=GUZUNQDNJPXMGG-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 53163   

TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53163(5-bromo-3-[2-(3-methylphenyl)hydrazinyl]indol-2-on...)
Affinity DataEC50:  6.83E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53163(5-bromo-3-[2-(3-methylphenyl)hydrazinyl]indol-2-on...)
Affinity DataEC50:  2.69E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetDisintegrin and metalloproteinase domain-containing protein 10(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM53163(5-bromo-3-[2-(3-methylphenyl)hydrazinyl]indol-2-on...)
Affinity DataIC50: 6.95E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: Torrey Pines Institute for Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM53163(5-bromo-3-[2-(3-methylphenyl)hydrazinyl]indol-2-on...)
Affinity DataIC50: 6.95E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: Torrey Pines Institute for Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM53163(5-bromo-3-[2-(3-methylphenyl)hydrazinyl]indol-2-on...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human full length PDE4B expressed in insect SF21 cells using cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM53163(5-bromo-3-[2-(3-methylphenyl)hydrazinyl]indol-2-on...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Trypanosoma brucei full length PDEB1 expressed in insect SF21 cells using cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed