BDBM531532 4-[1-(cyclopropylmethyl)-5-({6-[4-(2-hydroxypropan-2-yl)-3,5-dimethyl-1H-pyrazol-1-yl]pyrimidin-4-yl}amino)-4-methyl-1H-pyrazol-3-yl]benzonitrile::US11208400, Example 165::US11208400, Example 322

SMILES Cc1nn(c(C)c1C(C)(C)O)-c1cc(Nc2c(C)c(nn2CC2CC2)-c2ccc(cc2)C#N)ncn1

InChI Key InChIKey=BDEDUGDTPMOBRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 531532   

TargetSodium-dependent phosphate transport protein 2A(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM531532(US11208400, Example 322 | 4-[1-(cyclopropylmethyl)...)
Affinity DataIC50: 3nMAssay Description:For measuring Npt2a activity in a cell based assay, a stable CHO cell line with inducible Npt2a expression was generated. Therefore, CHO T-Rex cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
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TargetSodium-dependent phosphate transport protein 2A(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM531532(US11208400, Example 322 | 4-[1-(cyclopropylmethyl)...)
Affinity DataIC50: 4nMAssay Description:For measuring Npt2a activity in a cell based assay, a stable CHO cell line with inducible Npt2a expression was generated. Therefore, CHO T-Rex cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent