BDBM531509 4-[1-(cyclopropylmethyl)-5-{(6-[5-(difluoromethyl)-3-methyl-1H-pyrazol-1-yl]pyrimidin-4-yl}amino)-4-methyl-1H-pyrazol-3-yl]benzonitrile::US11208400, Example 142

SMILES Cc1cc(C(F)F)n(n1)-c1cc(Nc2c(C)c(nn2CC2CC2)-c2ccc(cc2)C#N)ncn1

InChI Key InChIKey=MZNFHMLTZWDDIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531509   

TargetSodium-dependent phosphate transport protein 2A(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM531509(4-[1-(cyclopropylmethyl)-5-{(6-[5-(difluoromethyl)...)
Affinity DataIC50: 3nMAssay Description:For measuring Npt2a activity in a cell based assay, a stable CHO cell line with inducible Npt2a expression was generated. Therefore, CHO T-Rex cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent