BDBM531434 6-(4-chloro-3,5-dimethyl-1H-pyrazol-1-yl)-N-[5-(4-fluorophenyl)-1,4-dimethyl-1H-pyrazol-3-yl]pyrimidin-4-amine::US11208400, Example 67

SMILES Cc1nn(c(C)c1Cl)-c1cc(Nc2nn(C)c(c2C)-c2ccc(F)cc2)ncn1

InChI Key InChIKey=CRQLHXXFVKMOFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531434   

TargetSodium-dependent phosphate transport protein 2A(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM531434(US11208400, Example 67 | 6-(4-chloro-3,5-dimethyl-...)
Affinity DataIC50: 3.45nMAssay Description:For measuring Npt2a activity in a cell based assay, a stable CHO cell line with inducible Npt2a expression was generated. Therefore, CHO T-Rex cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent