BDBM5314 2,4-diaryloxazole deriv. 2c::N-{2-[5-(3-fluorophenyl)pyridin-3-yl]-4-phenyl-1,3-oxazol-5-yl}acetamide

SMILES CC(=O)Nc1oc(nc1-c1ccccc1)-c1cncc(c1)-c1cccc(F)c1

InChI Key InChIKey=FXRYQZIMCVOCEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5314   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM5314(N-{2-[5-(3-fluorophenyl)pyridin-3-yl]-4-phenyl-1,3...)
Affinity DataIC50: 5.70E+3nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed