BDBM5311 1-(3-{3-[(dimethylamino)methyl]piperidin-1-yl}propyl)-4-{3-phenylimidazo[1,2-a]pyridin-7-yl}-1,2-dihydropyridin-2-one::imidazopyridine 18d

SMILES CN(C)CC1CCCN(CCCn2ccc(cc2=O)-c2ccn3c(cnc3c2)-c2ccccc2)C1

InChI Key InChIKey=VXURXFPUZVZOQH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5311   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM5311(1-(3-{3-[(dimethylamino)methyl]piperidin-1-yl}prop...)
Affinity DataIC50: 67nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed