BDBM531028 (R)-N1-(3-amino-2- hydroxypropyl)-4-(4-(1,3- dihydroxypropan-2-yl)piperazin- 1-yl)-3-(2H-tetrazol-5- yl)benzene-1,2-disulfonamide::US11207312, Example 160
SMILES NC[C@@H](O)CNS(=O)(=O)c1ccc(N2CCN(CC2)C(CO)CO)c(-c2nn[nH]n2)c1S(N)(=O)=O
InChI Key InChIKey=KHOHRDFIYPATSQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 531028
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1.16nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
TargetVIM-1 metallo-beta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1.34nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 5.49nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair