BDBM530883 1-[2-(Azetidin-1-yl)ethyl]-3-methyl-6-[3- (trifluoromethyl)phenyl]imidazo[4,5-b]pyridin-2- one::US11207298, Example 18

SMILES COC1=Cc2ncc(CN3CCN(c4ccc(C(=O)CC5CN(c6ccccc6)C5)nc4)CC3)cc2CC1=O

InChI Key InChIKey=XWPZFKHGTYKVCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530883   

TargetPoly [ADP-ribose] polymerase 1(Human)
Haisco Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 530883BDBM530883(US20260027108, Compound 46)
Affinity DataIC50: 0.560nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent