BDBM5307 1-methanesulfonyl-4-[(4-{3-phenylimidazo[1,2-a]pyridin-7-yl}phenyl)methyl]piperazine::imidazopyridine 12d

SMILES CS(=O)(=O)N1CCN(Cc2ccc(cc2)-c2ccn3c(cnc3c2)-c2ccccc2)CC1

InChI Key InChIKey=VICXPDHKANRRSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5307   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM5307(1-methanesulfonyl-4-[(4-{3-phenylimidazo[1,2-a]pyr...)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed