BDBM530567 WO2022076495, EXAMPLE 13

SMILES CC(C)n1c2cc(ccc2n(-c2cccc(c2)C2CC2)c1=O)C(=O)NC1(C)CS(=O)(=O)C1

InChI Key InChIKey=GEUWTQJWYYBLBV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530567   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530567(WO2022076495, EXAMPLE 13)
Affinity DataIC50: 17nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495