BDBM530462 N-(5-Chloro-3-methyl-1H-pyrazol-4-yl)-5-fluoro-4-(3-((S*)-l-hydroxyethyl)-4-methyl-1H-pyrazol-1-yl)-2-(((M-1,1,1-trifluoropropan-2-yl)oxy)benzamide::WO2022070069, Example 5

SMILES C[C@H](O)c1nn(cc1C)-c1cc(O[C@@H](C)C(F)(F)F)c(cc1F)C(=O)Nc1c(C)n[nH]c1Cl

InChI Key InChIKey=CCDUTJJWLBOJAX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 530462   

LigandPNGBDBM530462(WO2022070069, Example 5 | N-(5-Chloro-3-methyl-1H-...)
Affinity DataIC50: 0.260nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070069

LigandPNGBDBM530462(WO2022070069, Example 5 | N-(5-Chloro-3-methyl-1H-...)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human DHODH using DHO and CoQ6 as substrate by DCIP dye based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed