BDBM530443 (R*)-7-Fluoro-6-(5-(1-hydroxyethyl)-1-methyl-1H-1,2,4-triazol-3-yl)-4-isopropyl- 2-(o-tolyl)phthalazin-1(2H)-one.::WO2022070068, Example 15

SMILES CC(C)c1nn(-c2ccccc2C)c(=O)c2cc(F)c(cc12)-c1cn(C)c(n1)[C@@H](C)O

InChI Key InChIKey=QRNWTLGPRHKLCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530443   

LigandPNGBDBM530443((R*)-7-Fluoro-6-(5-(1-hydroxyethyl)-1-methyl-1H-1,...)
Affinity DataIC50: 2.60nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068