BDBM530442 7-Fluoro-6-(2-(2-hydroxypropan-2-yl)-1-methyl-1H-imidazol-4-yl)-4-isopropyl-2- (o-tolyl)phthalazin-1(2H)-one.::WO2022070068, Example 14

SMILES CC(C)c1nn(-c2ccccc2C)c(=O)c2cc(F)c(cc12)-c1cn(C)c(n1)C(C)(C)O

InChI Key InChIKey=HQIBKKYBSKVEKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 530442   

LigandPNGBDBM530442(7-Fluoro-6-(2-(2-hydroxypropan-2-yl)-1-methyl-1H-i...)
Affinity DataIC50: 0.450nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530442(7-Fluoro-6-(2-(2-hydroxypropan-2-yl)-1-methyl-1H-i...)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of human DHODH using dihydroorotate and CoQ6 as substrate by DCIP dye based spectrophotometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed